Zo'or (Anita La Selva) absorbs the contents of an ancient Taelon vial discovered near Ma'el's ship and suddenly collapses. The Taelon healer Mit'gai (Anaya Farrell) informs Liam Kincaid (Robert Leeshock) that Zo'or has contracted Pesh'tal, an ancient deadly plague for which there is no known cause or cure. Mit'gai warns that an epidemic could start among the Taelons, but the risk to humanity is unknown. Liam informs Renee Palmer (Jayne Heitmeyer) about Pesh'tal and she suggests using the virus to create a biological weapon to fight the Taelons. Renee and Liam recruit Augur (Richard Chevolleau) to research Pesh'tal and the possibilities of designing a weapon. Meanwhile at the Taelon Embassy, T'than (Michelle Nolden) is appointed by the Synod to oversee matters during Zo'or's incapacitation. Later, Liam pockets a vial of Zo'or's infected energy for Augur's research and Zo'or disappears.

Meanwhile at the Bushnell Psychiatric Institute, Kelly (Kerry McPherson) and Tom (Caley Wilson) sneak out while Dr. Elaine DeParis (Heather Hodgson) finishes bed checks. Zo'or portals to a park across the street from the Bushnell Institute and exchanges pleasantries with the newsstand proprietor Saied (Marvin Ishmael). Zo'or walks through the park and comes across Kelly and Tom, who suspect that Zo'or is lost. They bring Zo'or back to the institute and put him in an abandoned fallout shelter. Unbeknownst to Kelly and Tom, they are observed by Max (Shawn Ashmore), another patient at the hospital. Meanwhile, Mit'gai informs Liam that humans exposed to the virus are in danger and will experience psychotic episodes. He also tells Liam that Zo'or will eventually release enough neutron energy to cover a 50 mile radius that will cause a plague of madness and turn humans into homicidal psychopaths within in minutes.

Liam and Sandoval (Von Flores) learn that Zo'or is in New York City and Liam is approached by the newsstand proprietor Saied who informs Liam that Zo'or entered the Bushnell Institute. Liam becomes suspicious after talking to Tom, who is extremely nervous. Liam and Renee gain access to the hospital when they pose as a couple looking for accommodations for a relative. Max approaches Liam and tells him that he’s seen Zo'or.

Orderlies escort Max away and Liam and Renee leave the hospital believing that Zo'or is somewhere in the building. Meanwhile, T'than orders Sandoval to ensure that Zo'or is found dead and Sandoval accepts the position as T'than's Companion Protector. Later, Mit'gai develops anti-toxin patches for the virus and informs Sandoval that Zo'or will reach the lethal level of toxicity in a matter of hours. Meanwhile, Augur isolates the Pesh'tal virus, develops a Pesh'tal Geiger counter and pinpoints Zo'or's location at the hospital. Protected by the anti-toxin patches, Liam and Renee go to the institute. Max observes Tom and Kelly leaving the fallout shelter and informs Dr. DeParis. She and a couple of security guards find Zo'or and are zapped by an energy wave that pulses from Zo'or's body.

Liam and Renee discover Zo'or's hiding room, but Zo'or has left the shelter through another door and is running for the portal. Liam reaches Zo'or before he can get away and applies an anti-toxin patch to Zo'or's neck. After recovering, Zo'or confronts T'than about his ambitious plans and Renee confirms the anti-toxin patches negate any possibility of using the virus as a weapon against the Taelons.

This episode synopsis was originally produced by The Official E:FC Website and remains the property of Tribune Entertainment.