Renee Palmer (Jayne Heitmeyer) visits FBI director Hubble Urick (Frank Moore) at United Hospital, where he remains in a coma. Although Hubble's physician, Dr. Field (Jonathan Crombie), tells her there is no indication her good friend will recover, she remains hopeful. While leaving the facility, however, Renee comes across Reese Jackson (James Gallanders), a former Resistance fighter who abandoned the cause to start a family. He is at the hospital because his wife, Claire (Saskia Garel), is having surgery that will enable her to carry a child. Things go horribly wrong, and the hospital's Chief of Staff, Dr. Morrison (Maria Ricossa) enters the hospital room, telling Reese and Renee that Claire has had an allergic reaction to the anesthetic and has slipped into a coma. She has been taken to a germ-free coma ward.

Later that night in a hospital corridor, Reese and Renee overhear Morrison and a colleague talking about another patient that has slipped into a coma after having an allergic reaction. Suspicious, they sneak into the coma ward, where they find rows upon rows of comatose patients in stackable berth-like beds. Deducing that some sort of gas administered along with oxygen during surgery is causing the comas, they leave the ward to search for the hospital's oxygen supply. Acting FBI Director and Atavus collaborator Ryan Patricio (Noam Jenkins) visits Hubble's room, where he advises Dr. Field that he has been granted power of attorney over Hubble and his affairs. He orders the doctor to take Hubble off life support. The doctor reluctantly agrees to do so.

Back in the main wing of the hospital, Reese and Renee are in a corridor, when they overhear Morrison telling the wife of another patient that her husband has also fallen into a coma during surgery. Furious, Reese storms toward the doctor, demanding she tell the woman the truth. Instead, an orderly subdues Reese, injecting him with a sedative.

Hiding around a corner, Renee hears the doctor order Reese be taken to surgery for an emergency appendectomy. Realizing he is about to become the next coma victim, Renee hurries to find the operating room's source of oxygen, but is stopped by an orderly along the way. Sensing the orderly is really an Atavus, Renee shoots him and continues to the basement, where she finds the oxygen supply, along with a mysterious gas that is also being fed into the OR. She shuts off the valves, but Reese, in the operating room above her, has lost consciousness and is taken to the coma ward.

Renee again sneaks into the coma ward, where Reese is about to be put into one of the berths by an orderly. Renee shoots the orderly and rescues Reese as he regains consciousness. Renee quickly sets up a portable portal, while Reese searches for Claire. Suddenly, Ronald Sandoval (Von Flores) enters the ward with gun in hand, but Renee, Reese and the comatose Claire have already portaled to the safety of Augur's lair. There, J. Street (Melinda Deines) assists Dr. Qu (Derek Scott) as he tries to create an antidote that will save Claire. Learning from Renee that the hospital is infested with hybrids, he determines the coma-inducing substance is a mixture of oxygen and alien blood gases, and in order to develop a serum, he'll need an Atavus blood sample.

Renee and Reese return to the hospital, where they find a hybrid chamber from which an Atavus and a hybrid nurse emerge. Using a Freon gun to freeze the Atavus into submission, they take a blood sample. While Reese returns to the lair with the sample, Renee goes to find out what Sandoval has to do with Morrison's plot. She finds Sandoval with Morrison in the coma ward and watches in horror as they open a berth, inviting an Atavus to feed on the patient within. Realizing they are literally creating a food bank for the aliens, she races to Hubble's room and takes him to the lair by portal.

With the Atavus blood sample in hand, Dr. Qu is able to develop an effective serum for both Claire and Hubble. Just two weeks later, Hubble, who has returned to his duties as FBI Director, announces that Patricio has been arrested for collaborating with the Atavus, a new alien threat that can no longer be ignored. He also extends his gratitude to Renee for fighting the Atavus single-handedly.

This episode synopsis was originally produced by The Official E:FC Website and remains the property of Tribune Entertainment.